For laboratory and research use only. Not for human consumption.
FreePen Starter Kit+ free shipping over $200
Limitless Peptides
Cart
Home / Energy & Mitochondrial / MOTS-c
MOTS-C40 mg RUO

MOTS-c

Exercise in a vial, the mitochondrial peptide that flips your workout's AMPK switch.

  • Turns on AMPK, the metabolic master switch a hard workout flips, for real energy and endurance
  • A peptide the mitochondria write themselves, aimed straight at metabolic output
  • Now in its first human trial for blood sugar and body weight
Studied for
Energy and enduranceInsulin sensitivityMitochondrial function
≥99% purity HPLC-tested Energy & Mitochondrial
Size
$139per vial

Free shipping over $200 · ships from the USA

Why researchers choose it

MOTS-c is a peptide the body's own mitochondria, the tiny power plants inside every cell, make themselves. It switches on AMPK, the same energy sensor a hard workout flips, which is why it gets called an “exercise mimic” and why the research looks at energy, metabolism and blood-sugar control. It's still early: the first human trial testing whether it actually works is registered, but no results have been published yet.

Reconstitution reference concentration only, not dosing

Set the vial strength and how much bacteriostatic water you draw into it. This returns the resulting concentration for lab handling. It is a dilution reference, not a dosing recommendation.

mg / mL
Each 0.01 mL — one unit on a U-100 syringe — holds
Syringe drawVolumeAmount in that volume

Most compounds reconstitute with bacteriostatic water; a few acid-loving peptides use acetic acid instead. How much to draw, and how many vials a cycle needs, live in the Complete Peptide Guide, not here.

How much, and how many vials for a full cycle?

Protocol and cycle-length questions get answered in the Complete Peptide Guide, not here. These listings carry no dosing.

Read more →
This compound is supplied for laboratory research use only and is not for human or veterinary consumption. The research summarized here describes published third-party findings, not outcomes from Limitless Peptides, and is not dosing guidance or medical advice. These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

How to verify what you received

Every batch we list is third-party HPLC-tested to ≥99% purity. When your vial arrives, these are the handling and quality-control checks a researcher runs before use.

Commonly studied alongside

NAD+1000 mg RUO

NAD+(1000 mg)

Restores the cell-energy coenzyme that halves between age 20 and 50.

$89
SS-3150 mg RUO

SS-31(50 mg)

Recharges tired mitochondria, the first mito-targeted drug the FDA approved.

$169
VITAMIN B1210 mg RUO

Vitamin B12(10 mg)

Energy, focus and healthy nerves, the methylation vitamin you can't make.

$45

More in Energy & Mitochondrial

View all →
NAD+1000 mg RUO

NAD+(1000 mg)

Restores the cell-energy coenzyme that halves between age 20 and 50.

$89
SS-3150 mg RUO

SS-31(50 mg)

Recharges tired mitochondria, the first mito-targeted drug the FDA approved.

$169
VITAMIN B1210 mg RUO

Vitamin B12(10 mg)

Energy, focus and healthy nerves, the methylation vitamin you can't make.

$45

What the research reports 5 citations

  • Encoded in the 12S rRNA of mitochondrial DNA, making it one of the rare peptides the mitochondria write themselves.PubMed: MOTS-c
  • Activates AMPK, the same metabolic switch exercise flips, which is where the exercise-mimetic label comes from.PubMed: MOTS-c
  • The first human efficacy RCT is now registered: a Phase 2a in prediabetes with overweight/obesity.Phase 2a NCT07505745
  • A US compounding advisory committee voted 7-5 in July 2026 to recommend it for the 503A bulks list, advisory only with FDA rulemaking still pending.PCAC vote, Jul 2026
  • Documented contraindications are narrow but real: pregnancy, lactation, and active malignancy.researchdosing

Compound reference physicochemical facts

Class
Mitochondrial peptide
Molecular formula
C101H152N28O22S2
Molecular weight
2174.6 g/mol
CAS number
1627580-64-6
Storage
Lyophilized −20 °C; reconstituted 2–8 °C, kept from light
MOTS-c$139