5-Amino-1MQ

Oral fat-loss support that reboots cellular NAD+.

Releases the metabolic brake, blocks NNMT, the enzyme that drains NAD+ and slows fat metabolism
Lifts SIRT1 and AMPK, the two switches tied to fat loss and cellular energy
A stable small molecule, not a fragile peptide, so it holds potency far longer

Studied for

Fat metabolismNAD+ preservation

≥99% purity HPLC-tested Fat Loss & Metabolic

$109per vial

Free shipping over $200 · ships from the USA

Why researchers choose it

5-Amino-1MQ blocks NNMT, an enzyme that burns through NAD+, so blocking it is studied as a way to protect NAD+ and nudge fat metabolism through the SIRT1 and AMPK pathways. It's a stable small molecule rather than a fragile peptide, but every result so far comes from cell and animal studies.

Reconstitution reference concentration only, not dosing

Set the vial strength and how much bacteriostatic water you draw into it. This returns the resulting concentration for lab handling. It is a dilution reference, not a dosing recommendation.

Vial strength Bacteriostatic water added mL

—mg / mL

Each 0.01 mL — one unit on a U-100 syringe — holds —

Syringe draw	Volume	Amount in that volume

Most compounds reconstitute with bacteriostatic water; a few acid-loving peptides use acetic acid instead. How much to draw, and how many vials a cycle needs, live in the Complete Peptide Guide, not here.

How much, and how many vials for a full cycle?

Protocol and cycle-length questions get answered in the Complete Peptide Guide, not here. These listings carry no dosing.

This compound is supplied for laboratory research use only and is not for human or veterinary consumption. The research summarized here describes published third-party findings, not outcomes from Limitless Peptides, and is not dosing guidance or medical advice. These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

How to verify what you received

Every batch we list is third-party HPLC-tested to ≥99% purity. When your vial arrives, these are the handling and quality-control checks a researcher runs before use.

Appearance
A uniform white to off-white lyophilized cake or powder with a consistent fill. Copper peptides carry a characteristic blue tint.
Purity documentation
Our material is third-party HPLC-verified to ≥99% purity and identity before it is listed.
Sealed packaging
An intact flip-top seal and rubber stopper, with the compound and batch clearly labeled.
Clean reconstitution
Dissolves into a clear, particulate-free solution once bacteriostatic water is added.

Commonly studied alongside

NAD+(1000 mg)

Restores the cell-energy coenzyme that halves between age 20 and 50.

$89

MOTS-c(40 mg)

Exercise in a vial, the mitochondrial peptide that flips your workout's AMPK switch.

$139

What the research reports 5 citations

Inhibits nicotinamide N-methyltransferase (NNMT), the enzyme that consumes NAD+, which is why it is studied alongside NAD+ itself.PubMed: 5-Amino-1MQ
In preclinical work, that NNMT block raises SIRT1 and AMPK activity, the two switches tied to fat metabolism and cellular energy.Preclinical (cell and animal)
Reported half-life is 3.8 to 6.9 hours.researchdosing
It's a small molecule rather than a fragile peptide, so it holds structural stability well past the usual peptide window.Peptide Guide handling notes
Honest context: approved weight-loss drugs (semaglutide, tirzepatide, orforglipron) are far better proven for the same endpoint, and the NAD+ pathway effects here remain theoretical.Peptide Guide safety review

Compound reference physicochemical facts

Class: Small molecule (NNMT inhibitor)
Molecular formula: C₁₀H₁₁N₂+
Molecular weight: 159.21 g/mol
CAS number: 685079-15-6
Storage: Lyophilized −20 °C; reconstituted 2–8 °C, kept from light
Source: PubChem CID 950107

5-Amino-1MQ$109