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RETATRUTIDE10 mg RUO

Retatrutide

The most effective weight-loss peptide in human trials.

  • Triple-receptor agonism (GLP-1 + GIP + glucagon) engages three metabolic pathways at once, unlike single-target analogs
  • The most-studied next-generation metabolic peptide in current clinical research
  • Published trials report ~30% average body-weight reduction, with 45% of participants at 30% or more
Studied for
Body compositionAppetite regulationGlucose control
≥99% purity HPLC-tested Fat Loss & Metabolic
Size
$65per vial

Free shipping over $200 · ships from the USA

Why researchers choose it

Retatrutide hits three different weight-loss targets at once, GLP-1, GIP and glucagon, where other shots hit only one or two. In late-stage trials people lost close to 28% of their body weight, the biggest drop ever recorded for a weight-loss drug in humans. It isn't FDA-approved yet: the final Phase 3 trials are still wrapping up and no application has been filed.

Reconstitution reference concentration only, not dosing

Set the vial strength and how much bacteriostatic water you draw into it. This returns the resulting concentration for lab handling. It is a dilution reference, not a dosing recommendation.

mg / mL
Each 0.01 mL — one unit on a U-100 syringe — holds
Syringe drawVolumeAmount in that volume

Most compounds reconstitute with bacteriostatic water; a few acid-loving peptides use acetic acid instead. How much to draw, and how many vials a cycle needs, live in the Complete Peptide Guide, not here.

How much, and how many vials for a full cycle?

Protocol and cycle-length questions get answered in the Complete Peptide Guide, not here. These listings carry no dosing.

Read more →
This compound is supplied for laboratory research use only and is not for human or veterinary consumption. The research summarized here describes published third-party findings, not outcomes from Limitless Peptides, and is not dosing guidance or medical advice. These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.

How to verify what you received

Every batch we list is third-party HPLC-tested to ≥99% purity. When your vial arrives, these are the handling and quality-control checks a researcher runs before use.

Commonly studied alongside

BACTERIOSTATICWATER10 ml RUO

Bacteriostatic Water(10 ml)

The standard peptide solvent. 0.9% benzyl alcohol.

$19

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What the research reports 5 citations

  • Hits three receptors at once: GLP-1R for appetite, GIPR for insulin and fat, and GcgR for thermogenesis and hepatic fat.PubMed: Retatrutide
  • TRIUMPH-1 (obesity, 80 weeks): 28.3% weight loss at the highest trial dose, rising to 30.3% at 104 weeks, with 45.3% of participants losing at least 30% of body weight, a surgical-level result.TRIUMPH-1 (Phase 3, 80 wks)
  • TRIUMPH-4 (obesity plus knee osteoarthritis, 68 weeks): 28.7% at the top dose and 26.4% one step below it.TRIUMPH-4 (Phase 3, 68 wks)
  • TRANSCEND-T2D-1 in diabetes reported A1c down 2.0 points alongside 16.8% weight loss.TRANSCEND-T2D-1, Lancet Jun 2026
  • Phase 3 surfaced a dose-dependent abnormal-skin-sensation signal that was not seen in Phase 2.Phase 3 TRIUMPH warnings

Compound reference physicochemical facts

Class
GLP-1 / GIP / glucagon triple-agonist peptide
Storage
Lyophilized −20 °C; reconstituted 2–8 °C, kept from light
Retatrutide$65